![]() Human CD34 + stem cells express the hiwi gene, a human homologue of the Drosophila gene piwi. Role of the ZWILLE gene in the regulation of central shoot meristem cell fate during Arabidopsis embryogenesis. Moussian, B., Schoof, H., Haecker, A., Jurgens, G. A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells. The TGF-β signalling pathway is essential for Drosophila oogenesis. A niche maintaining germ line stem cells in the Drosophila ovary. A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary. Spectrosomes and fusomes anchor mitotic spindles during asymmetric germ cell divisions and facilitate the formation of a polarized microtubule array for oocyte specification in Drosophila. Morphogenesis of the Drosophila fusome and its implications for oocyte specification. Yb modulates the divisions of both germline and somatic stem cells through piwi- and hh-mediated mechanisms in the Drosophila ovary. ![]() Germline stem cell division and egg chamber development in transplanted Drosophila germaria. Drosophila ovary morphogenesis: analysis of terminal filament formation and identification of a gene required for this process. The germinal proliferation center in the testis of Drosophila melanogaster. Somatic control over the germline stem cell lineage during Drosophila spermatogenesis. Somatic support cells restrict germline stem cell self-renewal and promote differentiation. Decapentaplegic is essential for the maintenance and division of the germline stem cells in the Drosophila ovary. The germ line regulates somatic cyst cell proliferation and fate during Drosophila spermatogenesis. Identification and behavior of epithelial stem cells in the Drosophila ovary. The mouse homolog of Drosophila vasa is required for the development of male germ cells. Regulation of cell fate decision of undifferentiated spermatogonia by GDNF. Transforming growth factor beta signal transducer Smad2 is expressed in mouse meiotic germ cells, Sertoli cells, and Leydig cells during spermatogenesis. Requirement of Bmp8b for the generation of primordial germ cells in the mouse. Bmp4 is required for the generation of primordial germ cells in the mouse embryo. β1- and α6-integrin are surface markers on mouse spermatogonial stem cells. Regulation of proliferation and differentiation in spermatogonial stem cells. Remodeling of the postnatal mouse testis is accompanied by dramatic changes in stem cell number and niche accessibility. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Pattern and kinetics of mouse donor spermatogonial stem cell colonization in recipient testes. ![]() Computer assisted image analysis to assess colonization of recipient seminiferous tubules by spermatogonial stem cells from transgenic donor mice. Development of germ cell transplants in mice. Spermatogenesis following male germ-cell transplantation. & Gottlieb, D.) 149–187 (Cold Spring Harbor Press, Cold Spring Harbor, 2001).īrinster, R. The relationship between the spleen colony-forming cell and the haemopoietic stem cell. ![]()
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